Computer-aided applications in pharmaceutical technology by Jelena Djuris PDF

By Jelena Djuris

There is an ever starting to be desire for a rise within the wisdom of goods and methods in pharmaceutical know-how.  Analysis of knowledge is a vital a part of winning product and approach improvement and development.  Most information research tools now contain using computers.

This e-book serves to supply a few worthwhile info at the heritage of assorted computer-aided instruments, in addition to illustrative examples in their software in pharmaceutical know-how. Chapters disguise tools similar to experimental layout, multivariate research (chemometric tools), neural computing, computer-aided biopharmaceutic type, and computational fluid dynamics.

Show description

Read Online or Download Computer-aided applications in pharmaceutical technology PDF

Similar bioinformatics books

Albert Burger, Duncan Davidson, Richard Baldock's Anatomy Ontologies for Bioinformatics: Principles and PDF

This e-book presents a well timed and first-of-its-kind selection of papers on anatomy ontologies. it truly is interdisciplinary in its process, bringing jointly the proper services from computing and biomedical experiences. The publication goals to supply readers with a entire knowing of the rules of anatomical ontologies and the-state-of-the-art when it comes to present instruments and functions.

A. Malcolm Campbell's Discovering genomics, proteomics, and bioinformatics PDF

KEY profit: gaining knowledge of Genomics is the 1st genomics textual content that mixes net actions and case reviews with a problem-solving method of train upper-level undergraduates and first-year graduate scholars the basics of genomic research. extra of a workbook than a standard textual content, getting to know Genomics, moment variation permits scholars to paintings with actual genomic facts in fixing difficulties and offers the person with an lively studying event.

Get Single Cell Sequencing and Systems Immunology PDF

The quantity specializes in the genomics, proteomics, metabolomics, and bioinformatics of a unmarried telephone, in particular lymphocytes and on knowing the molecular mechanisms of platforms immunology. in accordance with the author’s own event, it presents revealing insights into the capability purposes, importance, workflow, comparability, destiny views and demanding situations of single-cell sequencing for determining and constructing disease-specific biomarkers as a way to comprehend the organic functionality, activation and disorder of unmarried cells and lymphocytes and to discover their useful roles and responses to treatments.

Read e-book online Understanding Clinical Data Analysis: Learning Statistical PDF

This textbook includes ten chapters, and is a must-read to all clinical and wellbeing and fitness pros, who have already got uncomplicated wisdom of ways to investigate their medical information, yet nonetheless, ask yourself, after having performed so, why techniques have been played the best way they have been. The publication can also be a must-read to people who are likely to submerge within the flood of novel statistical methodologies, as communicated in present scientific reviews, and medical conferences.

Extra resources for Computer-aided applications in pharmaceutical technology

Example text

G. material attributes) and process parameters that have been demonstrated to provide assurance of quality is denoted as the design space. The emphasis of the ICH Q8 guideline is to shift pharmaceutical product development from the empirical, trial-and-error approach, to the scientifically based process of design space appointment. Definition of design space also requires implementation of various risk management tools, as well as definition of specifications and manufacturing controls. 1 shows a diagram of a QbD approach, combining design space development and risk management tools.

9% was estimated, depending on the output critical values used for the classification. The low error rate demonstrated the success in employing ANNs to predict phase behavior of quaternary systems. The fundamental goal in SMEDDS development is to optimize the surfactant/cosurfactant/oil mixture, in order to achieve sufficient drug solubility and infinite dilutability with water phase. , 2010). The study of Mendyik and Jachowicz (2006) describes the development of the system 24 Published by Woodhead Publishing Limited, 2013 Computer-aided formulation development of 11 ANN models suitable for further prediction of phase behavior of microemulsion-forming systems analyzing only the properties and contents of the components.

2008). The pioneer studies of Richardson et al. (1996, 1997) demonstrated the use of ANNs to identify the physicochemical properties of the cosurfactant with relevance for microemulsion formation in the four-component system lecithin, (surfactant)/isopropyl myristate (oil)/triple distilled water/cosurfactant. e. short- and medium-chain alcohols, amines, acids, and ethylene glycol monoalkyl ethers) were employed. The BP feed-forward algorithm of learning and four computed cosurfactant molecule properties (molecular volume (v), areas for its head group (aψ) and hydrophobe (aφ), and computed octanol/water logP value), were selected.

Download PDF sample

Rated 4.16 of 5 – based on 17 votes